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Clinical Specialist – Variant Scientist

UCLA HEALTH

This is a Contract position in Los Angeles County, CA posted May 14, 2019.

Responsibilities The Department of Pathology and Laboratory Medicine at the University of California, Los Angeles, is seeking an Assistant Project Scientist to work with the Molecular Diagnostics Laboratories as a Variant Scientist.

The incumbent needs to have the ability to independently run bioinformatics pipeline, and interpret and draft reports for clinical findings from high throughput molecular diagnostic testing including exome and cancer panel sequencing.

The incumbent will be a key member of a clinical team of clinical laboratory scientists, molecular biologists, medical geneticists, and bioinformaticians working together to analyze new and archival clinical cases based on our high throughput sequencing assays.

The successful applicant will operate in three major areas: (1) clinical testing: participate in the review of patient clinical notes and sequencing data from high-complexity tests such as Clinical Exome Sequencing and the Hematologic Malignancies Sequencing Panel; (2) data curation and archiving: perform, review, organize variant curation, and database phenotype and variants of current cases and archival cases; (3) research and development: participate in variant submission to public databases, test development and clinical research projects.

This position is based on the UCLA campus in Westwood.

Qualifications A Ph.D.

degree in genetics (e.g.

human genetics, molecular genetics, neurogenetics) or cancer-related fields (e.g.

cancer cell biology, cellular and molecular pathology, molecular cancer biology, molecular and medical pharmacology) is preferred.

Background and expertise in bioinformatics, cancer genetics, and/or human genetics will be strongly preferred.

Candidates with a Master’s degree in molecular biology, genetics, bioinformatics, computational biology, or other related fields may be considered.

Incumbent demonstrates a strong intuitive understanding of probability.

Though laboratory techniques are not physically performed, you must understand the molecular biology of laboratory genetics and genomics (e.g.

target capture/amplification and massively parallel sequencing).

Excellent communication and writing skills required.

Strong ability to collaborate with teams of clinicians, research scientists, and external collaborators required.

Exhibits scientific creativity and routinely demonstrates independent thought.

Computer fluency is required (e.g.

MS Excel, IGV, UCSC/COSMIC genome browsers).

Computer programming (e.g.

R/SAS/Perl/Python), regex, database design, and/or bioinformatics experience would be a plus.